Mouse Anti-Human VEGFR-1/Flt-1 Antibody | 101-M24/101-MBi24

Mouse Anti-Human VEGFR-1/Flt-1 Antibody | 101-M24/101-MBi24 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#EWC)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: vascular endothelial growth factor receptor-1; FLT1; VEGF receptor 1;

Isotype: IgG1

Application: ELISA, WB, IF

Detection Range: ELISA: Use 1–10 µg/ml; Western blotting: Use at 2–5 µg/ml; The monoclonal antibody will detect native and denatured human VEGFR-1/Flt-1 in ELISA experiments and on the surface of different human cell types.

Species Reactivity/Cross reactivity: Human, mouse

Antigen: Recombinant human soluble Flt-1 (D5)

Description: VEGFR-1 is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 2321