Mouse Fyn Antibody | 58-032

Mouse Fyn Antibody | 58-032 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Homology: Predicted species reactivity based on immunogen sequence: Bovine, Human, Pig, Rat

Immunogen: This Mouse Fyn antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-535 amino acids from the C-terminal region of mouse Fyn.

Research Area: Cancer, Neuroscience, Signal Transduction

Tested Application: WB

Application: For WB starting dilution is: 1:1000

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 61 kDa

Validation: N/A

Isoform: N/A

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Clonality: Polyclonal

Clone: N/A

Isotype: Rabbit Ig

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.

Concentration: batch dependent

Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Tyrosine-protein kinase Fyn, Proto-oncogene c-Fyn, p59-Fyn, Fyn

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.