Mouse Insrr Antibody (C-term) [AMM06442G]

Mouse Insrr Antibody (C-term) [AMM06442G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: Rat

Specificity: This Mouse Insrr antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1265-1295 amino acids from the C-terminal region of Mouse Insrr.

Cellular Localisation: Membrane; Single-pass type I membrane protein

Molecular Weight: 144875

Clone: Polyclonal

Gene Name: Insrr

Gene ID: 23920

Function: Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Summary: Tissue Location: Highly expressed in the islets as well as in pancreatic beta-cells.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Insulin receptor-related protein, IRR, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, Insrr, Irr