Mouse Ptk7 Antibody (C-term) [APR33041G]

Mouse Ptk7 Antibody (C-term) [APR33041G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This mouse Ptk7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 722-757 amino acids from the C-terminal region of mouse Ptk7.

Cellular Localisation: Membrane; Single-pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells

Molecular Weight: 117532

Clone: Polyclonal

Gene Name: Ptk7

Gene ID: 71461

Function: Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

Summary: Tissue Location: Expressed at high levels in lung and un-pregnant uterus among adult tissues, and in the tail, limbs, somites, gut and craniofacial regions among embryonic tissues

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000 WB--1:500

Synonyms: Inactive tyrosine-protein kinase 7, Protein chuzhoi, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, Ptk7