Description
Mouse RANKL protein | PRP1114 | Gentaur UK, US & Europe Distribution
Product Category: Cytology
Application: Cytokines
Product Type: Cytokines
Sequence: Amino acid sequence derived from Mouse RANKL isoform (O35235) (Pro143-Asp316) was expressed.
Activity: N/A
protein Lenght: The recombinant Mouse sRANKL consists of 174 amino acids (N-Met) and has a predicted molecular mass of 19 kDa. The apparent molecular mass of the Mouse sRANKL protein is approximately 19 kDa in SDS-PAGE under reducing conditions.
Preparation: E. coli
Purity: ≥ 98 % as determined by SDS-PAGE
Formulation: Lyophilized from sterile 20 mM Tris, 150 mM NaCl pH 8.0.
Kit Component: N/A
Features & Benefits : N/A
Molecular Weight: 19 kDa
Usage Note: Always centrifuge tubes before opening . It is recommended to centrifuge at 12, 000 rpm for 1 minute. Then reconstitute the lyophilized Mouse sRANKL protein with the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage Conditions: Lyophilized Mouse RANKL proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.122% HSA or BSA) . Please prevent freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature.
Background: Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG.Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
Alternative Names: N/A
Search Names: N/A
Tag: RANKL