Mouse Rpl13a Antibody (N-term) [APR31814G]

Mouse Rpl13a Antibody (N-term) [APR31814G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Rpl13a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-54 amino acids from the N-terminal region of mouse Rpl13a.

Cellular Localisation: N/A

Molecular Weight: 23464

Clone: Polyclonal

Gene Name: Rpl13a

Gene ID: 22121

Function: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions (By similarity) . Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: 60S ribosomal protein L13a, Transplantation antigen P198, Tum-P198 antigen, Rpl13a, P198, Tstap198-7