Mouse Sgk196 Antibody (C-term) [APR17446G]

Mouse Sgk196 Antibody (C-term) [APR17446G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Sgk196 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-273 amino acids from the C-terminal region of mouse Sgk196.

Cellular Localisation: Endoplasmic reticulum membrane; Single-pass type II membrane protein

Molecular Weight: 39969

Clone: Polyclonal

Gene Name: Pomk

Gene ID: 74653

Function: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc) -beta-1, 3-N-acetylglucosamine (GlcNAc) - beta-1, 4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1, 3-N-acetylglucosamine-beta-1, 4- (phosphate-6-) mannose) . Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O- mannose, suggesting that this disaccharide serves as the substrate recognition motif (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Protein O-mannose kinase, POMK, 271-, Protein kinase-like protein SgK196, Sugen kinase 196, Pomk, Sgk196