Mouse Stk10 Antibody (C-term) [APR17449G]

Mouse Stk10 Antibody (C-term) [APR17449G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Stk10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-696 amino acids from the C-terminal region of mouse Stk10.

Cellular Localisation: Cell membrane; Peripheral membrane protein

Molecular Weight: 111906

Clone: Polyclonal

Gene Name: Stk10

Gene ID: 20868

Function: Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Summary: Tissue Location: Expressed predominantly in lymphoid organs such as spleen, thymus, and bone marrow

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, Stk10, Lok