Mouse Znf260 Antibody (N-term) [APR32782G]

Mouse Znf260 Antibody (N-term) [APR32782G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Znf260 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-115 amino acids from the N-terminal region of mouse Znf260.

Cellular Localisation: Nucleus.

Molecular Weight: 46443

Clone: Polyclonal

Gene Name: Znf260

Gene ID: 26466

Function: Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator.

Summary: Tissue Location: Predominantly present in heart. Outside the heart, it is detected in embryonic and postnatal vascular smooth muscle cells and in epithelial cells of the lung, gut and kidney at sites of epithelial morphogenesis and in the spinal cord (at protein level)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Zinc finger protein 260, Zfp-260, Znf260, Zfp260