MRPL10 polyclonal Antibody | BS61591

MRPL10 polyclonal Antibody | BS61591 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: Mitochondria have their own translation machinery for production of 13 proteins that are required for oxidative phosphorylation. MRP-L10 (39S ribosomal protein L10, mitochondrial), also known as MRPL8, is a 261 amino acid protein that is a component of the large ribosomal subunit of the mitochondria. MRP-L10 is one of the 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. MRP-L10 is deacteylated in a NAD+- dependent manner by SIRT3, which is an event that contributes to the regulation of mitochondrial protein synthesis. The gene encoding MRP-L10 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MRPL10 polyclonal Antibody detects endogenous levels of MRPL10 protein.

Molecular Weight: ~ 29 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 39S ribosomal protein L10, mitochondrial; L10mt; MRP-L10; 39S ribosomal protein L8, mitochondrial; L8mt; MRP-L8

Immunogen: Synthetic peptide, corresponding to amino acids 215-259 of Human MRPL10.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: