MRPL22 Polyclonal Antibody | E-AB-19168

MRPL22 Polyclonal Antibody | E-AB-19168 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: MRPL22, 39S ribosomal protein L22, 39S ribosomal protein L22 mitochondrial precursor, 39S ribosomal protein L25, 39S ribosomal protein L25, mitochondrial, E030011D16Rik, HSPC158, L22mt, L25mt, mitochondrial, mitochondrial ribosomal protein L22, MRP L22, MRP L25, MRP-L22, MRP-L25, Mrpl22, RM22, RPML25

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human MRPL22

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A