MRPL40 Polyclonal Antibody | E-AB-19169

MRPL40 Polyclonal Antibody | E-AB-19169 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 39S ribosomal protein L40, 39S ribosomal protein L40 mitochondrial, 39S ribosomal protein L40, mitochondrial precursor, FLJ41774, L40mt, MGC9400, mitochondrial, Mitochondrial ribosomal protein L40, MRP 40, MRP L22, MRP-L40, MRP40, MRPL22, MRPL40, NLVCF, Nuclear localization signal containing protein deleted in velocardiofacial syndrome, Nuclear localization signal deleted in velocardiofacial syndrome, Nuclear localization signal-containing protein deleted in velocardiofacial syndrome, RM40, Up-regulated in metastasis, URIM

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Metabolism

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.

Concentration: 1.44 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human MRPL40

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 24 kDa

Molecular Weight(Observed): Refer to figures