MT-ND1 Polyclonal Antibody | E-AB-13427

MT-ND1 Polyclonal Antibody | E-AB-13427 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Complex I, subunit ND1, Mitochondrially encoded NADH dehydrogenase 1, MT-ND1, MTND1, NAD1, NADH dehydrogenase subunit 1 (complex I), NADH dehydrogenase subunit 1, NADH-ubiquinone oxidoreductase chain 1, NADH-ubiquinone oxidoreductase, subunit ND1, NADH1, ND1, NU1M

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MT-ND1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 36 kDa

Molecular Weight(Observed): N/A