MTS Reagent | 2808

MTS reagent is a tetrazolium inner salt useful for determining the number of viable cells in proliferation or chemosensitivity assays. MTS is bioreduced by cells into a colored formazan product that is soluble in tissue culture medium. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes in metabolically active cells.

MTS reagent is a tetrazolium inner salt useful for determining the number of viable cells in proliferation or chemosensitivity assays. MTS is bioreduced by cells into a colored formazan product that is soluble in tissue culture medium. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes in metabolically active cells.

2808 | MTS Reagent DataSheet

Alternate Name/Synonyms: 3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; Owen’s reagent; MTSReagent powder

Appearance: Yellow solid

Formulation: N/A

CAS Number: 138169-43-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₇N₅O₆S₂

Molecular Weight: 487.51

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: DMSO or DPBS (2 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A cell proliferation assay reagent

MDL Number: N/A

PubChem CID: N/A

SMILES: O=C(O)COC1=CC=CC(C2=NN(C3=CC=C(S(=O)([O-])=O)C=C3)[N+](C4=NC(C)=C(C)S4)=N2)=C1

InChi: InChI=1S/C20H17N5O6S2/c1-12-13(2)32-20(21-12)25-23-19(14-4-3-5-16(10-14)31-11-18(26)27)22-24(25)15-6-8-17(9-7-15)33(28,29)30/h3-10H,11H2,1-2H3,(H-,26,27,28,29,30)

InChi Key: APRZHQXAAWPYHS-UHFFFAOYSA-N