MTTP polyclonal Antibody | BS6672

MTTP polyclonal Antibody | BS6672 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: Microsomal triglyceride transfer protein (MTP), catalyzes the transport of cholesteryl ester, triglyceride and phospholipid between phospholipid surfaces. MTP is a heterodimer consisting of MTP and PDI (protein disulfide isomerase) . It is required for the secretion of plasma lipoproteins containing apolipoprotein b. It is negatively regulation by insulin and positively regulated by cholesterol. MTP, which localizes to the endoplasmic reticulum (ER), is expressed primarily in small intestine and liver, kidney, testis and ovary. It is not expressed in epithelial cells. Defects in the MTP gene can cause abetalipoproteinemia (ABL) which is an autosomal recessive lipoprotein metabolism disorder.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MTTP polyclonal Antibody detects endogenous levels of MTTP protein.

Molecular Weight: ~ 99 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ABL; Microsomal triglyceride transfer protein; Microsomal triglyceride transfer protein large subunit; MTP; MTTP;

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human MTTP (NP_000244.2) .

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: