Muristerone A | 2184

A potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A (Cat. No. 2183). Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Induces expression of β-galactosidase. Induces apoptosis in cells transfected with wild-type Bax. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.

Muristerone A is a potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A (Cat. No. 2183). Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals.

2184 | Muristerone A DataSheet

Alternate Name/Synonyms: 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 38778-30-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₇H₄₄O₈

Molecular Weight: 496.63

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An Ecdysone receptor (EcR) agonist

MDL Number: MFCD00056450

PubChem CID: 122217

SMILES: CC(C)CCC(C(C)(C1CCC2(C1(CC(C3C2=CC(=O)C4(C3(CC(C(C4)O)O)C)O)O)C)O)O)O

InChi: InChI=1S/C27H44O8/c1-14(2)6-7-20(31)25(5,33)19-8-9-26(34)15-10-21(32)27(35)13-17(29)16(28)11-24(27,4)22(15)18(30)12-23(19,26)3/h10,14,16-20,22,28-31,33-35H,6-9,11-13H2,1-5H3/t16-,17+,18+,19-,20+,22+,23+,24+,25+,26+,27+/m0/s1

InChi Key: LRJUYAVTHIEHAI-LHBNDURVSA-N