223

MYC Antibody | XW-7756

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SKU:
223-XW-7756-GEN
NULL858.00

Description

MYC Antibody | XW-7756 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: 410-419

Research Area: Other

Tested Application: E, WB

Application: Myc proto-oncogene protein antibody can be used for the detection of Myc proto-oncogene protein by ELISA and Western Blot, may also work for ICC and IHC.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 48.8 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: MYC antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: BHLHE39, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, MRTL, MYCC, c-Myc, Myc protooncogene protein, Transcription factor p64

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes.

DISEASE: A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t (8;12) (q24;q22) with BTG1.

SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C.

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Additional Information

Size:
0.05 mg
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