Description
MYC Antibody | XW-7756 | Gentaur UK, US & Europe Distribution
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: 410-419
Research Area: Other
Tested Application: E, WB
Application: Myc proto-oncogene protein antibody can be used for the detection of Myc proto-oncogene protein by ELISA and Western Blot, may also work for ICC and IHC.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 48.8 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: MYC antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: BHLHE39, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, MRTL, MYCC, c-Myc, Myc protooncogene protein, Transcription factor p64
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes.
DISEASE: A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t (8;12) (q24;q22) with BTG1.
SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C.