MYD88 monoclonal Antibody | MB64095

MYD88 monoclonal Antibody | MB64095 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Rat

Application: FC, IF, WB

Application Range: WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: myeloid differentiation primary response 88

Molecular Weight: 33.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MYD88D

Immunogen: Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A