MyD88 Polyclonal Antibody | BS65652

MyD88 Polyclonal Antibody | BS65652 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,

Application: WB,

Application Range: WB=1:500-2000

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.

Molecular Weight: 36 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: myeloid differential protein-88; Myeloid differentiation primary response gene; MYD 88; MYD88D; Myeloid differentiation marker 88; Myeloid differentiation primary response gene 88; Myeloid differentiation primary response gene; Myeloid differentiation primary response protein MyD88; MYD 88; Myd88; MYD88_HUMAN; OTTHUMP00000161718; OTTHUMP00000208595; OTTHUMP00000209058; OTTHUMP00000209059; OTTHUMP00000209060.

Immunogen: KLH conjugated synthetic peptide derived from mouse MyD88

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: