MYOF Antibody | 16-042

MYOF Antibody | 16-042 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_038479.1) .

Research Area: Cell Cycle

Tested Application: WB

Application: WB: 1:200 - 1:2000

Specificiy: N/A

Positive Control 1: U-251MG

Positive Control 2: A-549

Positive Control 3: HeLa

Positive Control 4: NIH/3T3

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 250kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: FER1L3, myoferlin, fer-1-like 3, myoferlin, fer-1-like family member 3, fer-1-like protein 3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.