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NBPF12 polyclonal Antibody | BS61787
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- BW-BS61787
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Description
NBPF12 polyclonal Antibody | BS61787 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: NBPF12 pAb detects endogenous levels of NBPF12 protein.
Molecular Weight: ~ 99-140 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Neuroblastoma breakpoint family member 12; Chromosome 1 amplified sequence 1; NBPF12; COAS1; KIAA1245; Neuroblastoma breakpoint family member 10; NBPF10; Neuroblastoma breakpoint family member 15; Neuroblastoma breakpoint family member 16; NBPF15; NBPF16; Neuroblastoma breakpoint family member 1; NBPF1; KIAA1693; Neuroblastoma breakpoint family member 9; NBPF9; Neuroblastoma breakpoint family member 20; NBPF20; Neuroblastoma breakpoint family member 14; NBPF14
Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human NBPF12.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: