NCAM-L1 (R1177) polyclonal Antibody | BS3723

NCAM-L1 (R1177) polyclonal Antibody | BS3723 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background: The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius) ; 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs) ; and 3) SPG1 (spastic paraplegia) . The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NCAM-L1 (R1177) polyclonal Antibody detects endogenous levels of NCAM-L1 protein.

Molecular Weight: ~ 140 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MIC 5; antigen identified by monoclonal Antibody R1; MASA; CD 171; MIC5; N CAML1; SPG1; N CAM L1; HSAS; CD171; CD171 antigen; SPG 1; L1 cell adhesion molecule; HSAS1; HGNC:7086; NEURAL CELL ADHESION MOLECULE L1 PRECURSOR; S10; CAML1

Immunogen: Synthetic peptide, corresponding to amino acids 1150-1200 of Human NCAM-L1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Epigenetic Writers and Erasers of Histone H3,