NDUFA1 polyclonal Antibody | BS60474

NDUFA1 polyclonal Antibody | BS60474 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: NDUFA1 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1), also known as ZNF183 or MWFE, is one of about 45 subunits comprising Complex I of the oxidative phosphorylation electron transport chain. Consisting of 70 amino acids and expressed predominantly in skeletal muscle and heart, NDUFA1 functions as an accessory subunit of the multi-protein mitochondrial membrane respiratory chain NADH dehydrogenase complex (known as Complex I) . Complex I plays an important role in the transfer of electrons from NADH to the respiratory chain, a process that is essential for cellular respiration. As a single-pass membrane protein, NDUFA1 localizes to the matrix side of the mitochondrial inner membrane and is a member of the complex I NDUFA1 subunit family. The gene encoding NDUFA1 maps to human chromosome Xq24 and mouse chromosome X A2. NDUFA1 defects may cause mitochondrial Complex I deficiency, a mitochondrial disorder with wide symptoms ranging from cardiomyopathy, myopathy, liver disease and neurological disorders.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NDUFA1 polyclonal Antibody detects endogenous levels of NDUFA1 protein.

Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; Complex I-MWFE; CI-MWFE; NDUFA1

Immunogen: A synthetic peptide corresponding to residues in Human NDUFA1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Epigenetic Writers and Erasers of Histones H2A H2B and H4,