NDUFS2 Antibody, KO Validated | 14-668

NDUFS2 Antibody, KO Validated | 14-668 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human NDUFS2 (NP_004541.1) .

Research Area: Cancer, Cell Cycle, Neuroscience, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: LO2

Positive Control 2: HeLa

Positive Control 3: 293T

Positive Control 4: Mouse brain

Positive Control 5: Mouse kidney

Positive Control 6: Mouse spleen

Molecular Weight: Observed: 49kDa

Validation: Antibody is Knockout validated.

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: NDUFS2, NADH-ubiqui oxidoreductase NDUFS2 subunit, NADH dehydrogenase (ubiqui) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) , complex 1, mitochondrial respiratory chain, 49-KD subunit, CI-49

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.