NDUFS3 polyclonal Antibody | BS90921

NDUFS3 polyclonal Antibody | BS90921 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC ICC IF IP

Application Range: WB:1:500 IHC:1:50 ICC:1:50 IP:1:10-1:50

Background: NDUFS3 (NADH dehydrogenase ubiquinone iron-sulfur protein 3) is one of about 45 subunits comprising complex I of the oxidative phosphorylation electron transport chain. The multisubunit NADH: ubiquinone oxidoreductase (complex I) is the first enzyme complex in the electron transport chain of the mitochondria. NDUFS3 is the last subunit of the seven subunits that make up the core of complex I. Through use of chaotropic agents, complex I can be separated into three different fractions: a flavoprotein fraction, an iron-sulfur protein (IP) fraction, and a hydrophobic protein (HP) fraction. The IP fraction includes NDUFS1-7. NDUFS3 contains a highly conserved casein kinase II phosphorylation site. Mutations in the NDUFS3 gene may cause optic atrophy, Leigh syndrome and complex I deficiency.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: NDUFS3 polyclonal Antibody detects endogenous levels of NDUFS3 protein.

Molecular Weight: 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CI-30kD, NDUFS3, CI 30, CI 30KD, CI-30kD, Complex I 30KD, Complex I 30kDa subunit, COMPLEX I, MITOCHONDRIAL RESPIRATORY CHAIN, 30-KD SUBUNIT, Complex I-30kD, mitochondrial, NADH coenzyme Q reductase, NADH dehydrogenase (ubiquinone) Fe S protein 3 30kDa, NADH dehydrogenase [ubiquinone] iron sulfur protein 3 mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, NADH dehydrogenase ubiquinone 30 kDa subunit, NADH-ubiquinone oxidoreductase 30 kDa subunit, NADH-Ubiquinone Oxidoreductase Fe-S Protein 3, NDUFS3, NDUS3,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: