NEDD1 polyclonal Antibody | BS70668

NEDD1 polyclonal Antibody | BS70668 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200

Background: NEDD1 (neural precursor cell expressed, developmentally downregulated 1), also known as GCP-WD, is a homolog of the Drosophila protein known as Dgp71WD. It is a ubiquitously expressed, evolutionarily conserved protein and contains eight WD40 repeats and a coiled coil domain at the C-terminus. NEDD1 is a subunit of the γ-tubulin ring complex (γTuRC) and plays an important role in mitosis. During mitosis NEDD1 is phosphorylated and functions in forming the association of γ-tubulin with the spindle. The state of phosphorylation of NEDD1 is also important for determining its cellular localization. NEDD1 is responsible for targeting γTuRC to the centrosome and spindle and is therefore required for centrosomal and chromatin-mediated microtubule nucleation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NEDD1 polyclonal Antibody detects endogenous levels of NEDD1 protein.

Molecular Weight: ~ 72 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protein NEDD1

Immunogen: Recombinant protein of human NEDD1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: