NEFH monoclonal Antibody | MB64164

NEFH monoclonal Antibody | MB64164 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:2000

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: neurofilament, heavy polypeptide

Molecular Weight: 112.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CMT2CC; NFH

Immunogen: Human recombinant protein fragment corresponding to amino acids 778-1020 of human NEFH (NP_066554) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A