Neurofilament NF-L Antibody [DA2] | 50-255

Neurofilament NF-L Antibody [DA2] | 50-255 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat, Bovine, Chicken

Homology: N/A

Immunogen: Preparation of porcine intermediate filaments.

Research Area: Neuroscience

Tested Application: WB, IHC

Application: N/A

Specificiy: Specific for the ~68k Neurofilament L protein.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 68

Validation: N/A

Isoform: N/A

Purification: Total IgG fraction

Clonality: Monoclonal

Clone: DA2

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: N/A

Concentration: N/A

Storage Condition: Neurofilament NF-L antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.

Alternate Name: N/A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Neurofilaments are the 10nm or intermediate filament proteins specifically in neurons, and are composed predominantly of three major proteins called NF- NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.