NEUROG1 polyclonal Antibody | BS60557

NEUROG1 polyclonal Antibody | BS60557 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The neurogenin family of proteins belongs to the basic helix-loop-helix (bHLH) superfamily and consists of neurogenin 1, neurogenin 2 and neurogenin 3 (also designated ngn3) . bHLH members are transcriptional regulators that determine cell fate. During mouse neurogenesis, Neurogenin 1 and Neurogenin 2 are expressed in distinct progenitor populations in the central and peripheral nervous systems. Targeted mutation analyses have shown that Neurogenin 1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia and that Neurogenin 2 is essential for the determination of precursors for epibranchial placode-derived sensory neurons. The gene which encodes Neurogenin 1 maps to human chromosome 5q23-q31.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NEUROG1 polyclonal Antibody detects endogenous levels of NEUROG1 protein.

Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Neurogenin-1; NGN-1; Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3; NEUROG1; BHLHA6; NEUROD3; NGN; NGN1

Immunogen: A synthetic peptide corresponding to residues in Human NEUROG1

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A