NFκB-p100 Polyclonal Antibody | E-AB-12803

NFκB-p100 Polyclonal Antibody | E-AB-12803 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CVID10, DNA binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10 protein, LYT 10, NF kB2, NFKB p52/p100 subunit, Nuclear factor Kappa B subunit 2, Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100), Nuclear factor of kappa light polypeptide gene enhancer in B cells 2, Oncogene Lyt 10, p100, Transcription factor NFKB2

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human NFKB2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 97 kDa

Molecular Weight(Observed): N/A