NFKBIZ Polyclonal Antibody | E-AB-53316

NFKBIZ Polyclonal Antibody | E-AB-53316 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FLJ30225, FLJ34463, I-kappa-B-zeta, Ikappa B zeta, IkappaB zeta, IkappaBzeta, IkB-zeta, IKBZ, IKBZ, IKBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, MAIL, MAIL protein, Molecule possessing ankyrin repeats induced by lipopolysaccharide, NF-kappa-B inhibitor zeta, NFKBIZ, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology

Background: This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human NFKBIZ

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 78 kDa

Molecular Weight(Observed): Refer to figures