Description
NG 52 (Compound 52 ) is a potent, selective, cell-permeable, and reversible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC₅₀ = 7 μM), and the related Pho85p kinase (IC₅₀ = 2 μM).
NG 52 (Compound 52 ) is a potent, selective, cell-permeable, and reversible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC₅₀ = 7 μM), and the related Pho85p kinase (IC₅₀ = 2 μM).
Alternate Name/Synonyms: 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-ethanol; compound 52
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 212779-48-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₉ClN₆O
Molecular Weight: 346.81
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, selective Cdc28p inhibitor
MDL Number: N/A
PubChem CID: 2856
SMILES: CC(C)N1C=NC2=C1N=C(N=C2NC3=CC(=CC=C3)Cl)NCCO
InChi: InChI=1S/C16H19ClN6O/c1-10(2)23-9-19-13-14(20-12-5-3-4-11(17)8-12)21-16(18-6-7-24)22-15(13)23/h3-5,8-10,24H,6-7H2,1-2H3,(H2,18,20,21,22)
InChi Key: XZEFMZCNXDQXOZ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |