NGF-beta, human recombinant | 4303R

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NGF-β is a dimer, formed by two identical 119 amino acid subunits, which is held together by strong hydrophobic interactions. Recombinant human BGF-b produced in CHO cells is a homodimer, glycosylated, polypeptide chain containing 2 identical 119 amino acids and having a molecular weight of 16.95 kDa. The protein is purified by proprietary chromatographic techniques.

4303R | NGF-beta, human recombinant DataSheet

Biomolecule/Target :NGF-beta

Synonyms: β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.

Alternates names: β Polypeptide, NGF, NGFB, HSAN5, β-NGF, MGC161426, MGC161428.

Taglines: A factor critical for the survival & maintenance of sympathetic and sensory neurons

NCBI Gene ID #: 4803

NCBI Gene Symbol: NGF

Gene Source: Human

Accession #: P01138

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGE: ≥97%

Assay: SDS-PAGE

Purity: ≥97%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/ug

Activity (Specifications/test method): N/A

Biological activity: The EDâ‚…â‚€ as determined by the ability to stimulate neurite growth in chick E9 DRG cells is <1.0 ng/ml.

Results: 0.8 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 13.6 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and then lyophilized with no additives.

Reconstitution Instructions: Reconstituted human NGF-β should be stored in working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles.

Amino acid sequence: N/A

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans