NGFR p75 (K279) polyclonal Antibody | BS2826

NGFR p75 (K279) polyclonal Antibody | BS2826 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC: 1:50~1:200

Background: NGFR p75 is a 75kD transmembrane glycoprotein (399 a.a.) consisting of an extracellular domain (222 a.a.) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22 a.a.), and a cytoplasmic domain (155 a.a.) . NGFR p75 is mainly expressed in Schwann cells and neurons and in a variety of non neuronal cells. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NGFR p75 (K279) polyclonal Antibody detects endogenous levels of NGFR p75 protein.

Molecular Weight: ~ 45,75 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16

Immunogen: Synthetic peptide, corresponding to amino acids 251-300 of Human NGFR p75.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Actin Dynamics,Warburg Effect,Inhibition of Apoptosis,Mitochondrial Control of Apoptosis,