NHEDC2 Polyclonal Antibody | BS65471

NHEDC2 Polyclonal Antibody | BS65471 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Rabbit,

Application: WB,

Application Range: WB=1:500-2000

Background: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NHEDC2 Polyclonal Antibody detects endogenous levels of NHEDC2 protein.

Molecular Weight: 53 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NHA2; Mitochondrial Na (+) /H (+) exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na (+) /H (+) exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain containing protein 2; NHE10; NHEDC 2; Sodium/hydrogen exchanger like domain containing protein 2; SL9B2_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human NHEDC2:151-250/537

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: