223

NIPSNAP2 Antibody | 4953

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SKU:
223-4953-GEN
NULL341.00 - NULL647.00

Description

NIPSNAP2 Antibody | 4953 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: NIPSNAP2 antibody was raised against a 14 amino acid synthetic peptide near the center of human NIPSNAP2.
The immunogen is located within the first 50 amino acids of NIPSNAP2.

Research Area: Neuroscience

Tested Application: E, WB, IHC-P

Application: NIPSNAP2 antibody can be used for detection of NIPSNAP2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1375 - Human Skeletal Muscle Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: NIPSNAP2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: NIPSNAP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: NIPSNAP2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: NIPSNAP2 Antibody: NIPSNAP2, NIPSNAP2, Protein NipSnap homolog 2, Glioblastoma-amplified sequence, NipSnap2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: NIPSNAP2 Antibody: The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.

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