NKAP Antibody (C-term) [APR30945G]

NKAP Antibody (C-term) [APR30945G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.

Cellular Localisation: Nucleus.

Molecular Weight: 47138

Clone: Polyclonal

Gene Name: NKAP

Gene ID: 79576

Function: Acts as a transcriptional repressor (PubMed:14550261, PubMed:19409814, PubMed:31587868) . Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development (PubMed:19409814) . Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch- regulated SKP2 promoter.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: NF-kappa-B-activating protein, NKAP