NKX2-6 Antibody | 6751

NKX2-6 Antibody | 6751 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: NKX2-6 antibody was raised against a 15 amino acid synthetic peptide near the center of human NKX2-6.
The immunogen is located within amino acids 170 - 220 of NKX2-6.

Research Area: Stem Cell

Tested Application: E, WB, IHC-P, IF

Application: NKX2-6 antibody can be used for detection of NKX2-6 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms

Positive Control 1: Cat. No. 1401 - Mouse Heart Tissue Lysate

Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: NKX2-6 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: NKX2-6 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: NKX2-6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: NKX2-6 Antibody: CSX2, NKX2F, NKX4-2, Homeobox protein NK-2 homolog F

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: NKX2-6 Antibody: NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.