NNT-1/BCSF-3, Human Recombinant | P1332

NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member (LIFR-) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Human Recombinant NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.

P1332 | NNT-1/BCSF-3 Human Recombinant DataSheet

Biomolecule/Target: NNT-1/BCSF-3

Synonyms: Novel Neurtrophin-1, NNT-1, B-Cell-Stimulating Factor-3, BSF-3, Cardiotrophin-like cytokine, Cardiotrophin-like cytokine factor 1 (CLCF1), CLCF1, BSF3, CLC, NNT1

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Taglines: Promotes the survival of chick embryonic motor and sympathetic neurons

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Gene Source: N/A

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Recombinant: Yes

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Binding Capacity: N/A

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Appearance: Lyophilized

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