Noopept | B2148

Noopept is a novel proline-containing dipeptide with nootropic and cognition-enhancing activity. Rescues α-synuclein amyloid toxicity in cellular models. Stimulates the expression of NGF and BDNF in rat hippocampus. Improves viability of hippocampal HT-22 neurons in a glutamate toxicity model. Normalizes blood glucose level and tolerance to glucose load in a streptozotocin diabetic rat model of developing diabetes.

Noopept is a novel proline-containing dipeptide with nootropic and cognition-enhancing activity. Rescues α-synuclein amyloid toxicity in cellular models. Stimulates the expression of NGF and BDNF in rat hippocampus. Improves viability of hippocampal HT-22 neurons in a glutamate toxicity model. Normalizes blood glucose level and tolerance to glucose load in a streptozotocin diabetic rat model of developing diabetes.

B2148 | Noopept DataSheet

Alternate Name/Synonyms: 1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester; or N-Phenylacetyl-L-prolylglycine ethyl ester; SGS-111; GVS 111

Appearance: White powder

Formulation: N/A

CAS Number: 157115-85-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₂N₂O₄

Molecular Weight: 318.4

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A nootropic and neuroprotective agent

MDL Number: MFCD00941121

PubChem CID: 180496

SMILES: CCOC(=O)CNC(=O)C1CCCN1C(=O)CC2=CC=CC=C2

InChi: InChI=1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1

InChi Key: PJNSMUBMSNAEEN-AWEZNQCLSA-N