NOSIP polyclonal Antibody | BS71005

NOSIP polyclonal Antibody | BS71005 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Endothelial nitric oxide synthase (eNOS) interacting protein (NOSIP) is a modulator of eNOS activity. eNOS is an important nitric oxide (NO) -generating enzyme of the vasculature that is regulated by interactions with caveolin-1, Ca2+-calmodulin, HSP 90 and NOSIP. NOSIP modulates this activity by promoting the translocation of eNOS from the plasma membrane to intracellular sites, which in turn inhibits NO synthesis. NOSIP is involved in controlling airway and vascular diameter, synthesis of NO in ciliated epithelia and mucosal secretion, and is an important protein for mucociliary and bronchial function. NOSIP is highly expressed in endothelial cells and vascularized tissue.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NOSIP polyclonal Antibody detects endogenous levels of NOSIP protein.

Molecular Weight: ~ 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CGI-25; Nitric oxide synthase-interacting protein

Immunogen: Recombinant protein of human NOSIP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: