Description
NQO1 Antibody | 33-029 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Research Area: Obesity, Signal Transduction
Tested Application: WB
Application: Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A affinity chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: NAD (P) H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD (P) H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: NAD (P) H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC or ���non-small cell lung cancer, ��� suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.