NS Antibody | XW-7166

NS Antibody | XW-7166 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: 1-280

Research Area: Homeostasis

Tested Application: WB

Application: E2IG3 antibody can be used for the detection of E2IG3 by Western blot, may also work for IHC and ICC.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 62 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Antigen affinity-purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: NS antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: E2IG3, NS, Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, NNP47, E2IG3, C77032

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Nucleostemin; putative nucleotide binding protein, estradiol-induced; E2IG3. This protein may play a role in maintaining stem cell self-renewal. Depletion or overexpression of nucleostemin reduces cell proliferation in CNS stem cells and transformed cells. Mutation analysis indicated that excessive nucleostemin, particularly mutants lacking the GTP-regulatory domain, prevents cells from entering mitosis and causes apoptosis in a p53-dependent manner. The N-terminal basic domain mediates the interaction with p53 and is required for the cell death caused by overexpression.