Description
NS6180 is a novel potent and selective KCa3.1 channel inhibitor (IC50= 9nM) prevents T-cell activation and inflammation.
NS6180 is a novel potent and selective KCa3.1 channel inhibitor (IC50= 9nM) prevents T-cell activation and inflammation.
Alternate Name/Synonyms: NS6180; NS 6180; NS-6180; 4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one
Appearance: Solid
Formulation: N/A
CAS Number: 353262-04-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₂F₃NOS
Molecular Weight: 323.33
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A novel potent and selective KCa3.1 channel inhibitor
MDL Number: NA
PubChem CID: 11837221
SMILES: C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F
InChi: 1S/C16H12F3NOS/c17-16(18,19)12-5-3-4-11(8-12)9-20-13-6-1-2-7-14(13)22-10-15(20)21/h1-8H,9-10H2
InChi Key: ZUIJXKLTUFCDGO-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |