NSD3 polyclonal Antibody | BS90970

NSD3 polyclonal Antibody | BS90970 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB FC

Application Range: WB:1:1,000-1:2,000 FC:1:50-1:100

Background: The deduced 1,437 amino acid NSD3 protein contains two PWWP domains involved in protein-protein interactions, five PHD-type zinc finger motifs found in chromatin-associated proteins, a SAC (SET-associated cys-rich) domain, a SET domain and a C-terminal C5HCH domain. Two NSD3 variants have been identified. The short variant comprised of 645 amino acids, arises from alternative polyadenylation and exon splicing and contains a single PWWP domain. A longer NSD3 variant, which is only expressed in HeLa cells, is comprised of 1,388 amino acid residues. The human WHSC1L1 gene, which encodes the NSD3 protein, shares 68% and 55% identity with mouse Nsd1 and human WHSC1, respectively. Highest expression of NSD3 is observed in brain, heart and skeletal muscle tissues; lower levels of NSD3 expression are observed in the liver and lungs.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: NSD3 polyclonal Antibody detects endogenous levels of NSD3 protein.

Molecular Weight: 162 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: WHSC1-like protein 1, WHSC1L1, DKFZp667H044, FLJ20353, Histone lysine N methyltransferase NSD3, Histone-lysine N-methyltransferase NSD3, MGC126766, MGC142029, NSD 3, NSD3, Nuclear set domain containing 3, Nuclear SET domain containing protein 3, Nuclear SET domain-containing protein 3, pp14328, Protein whistle, Whistle, WHSC1 like protein 1, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, WHSC1-like protein 1, WHSC1L1, WHSC1L1 protein, Wolf Hirschhorn syndrome candidate 1 like 1, Wolf-Hirschhorn syndrome candidate 1-like protein 1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: