NSUN6 polyclonal Antibody | BS8774

NSUN6 polyclonal Antibody | BS8774 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB: 1:500~1:2000 IF: 1:50~1:200

Background: The nucleolus consists of a number of specific proteins that play a critical role in the assembly of ribosomes, as well as in the maintenance and structural integrity of the nucleolus. NSUN6 ( NOL1/NOP2/Sun domain family member 6), also known as NOPD1 (NOL1/NOP2/Sun and PUA domain-containing protein 1), is a 469 amino acid protein that belongs to the methyltransferase superfamily. NSUN6 contains 1 PUA domain and may have S-adenosyl-L-methionine-dependent methyl-transferase activity. The gene encoding NSUN6 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: NSUN6 polyclonal Antibody detects endogenous levels of NSUN6 protein.

Molecular Weight: ~ 52kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Putative methyltransferase NSUN6; NOL1/NOP2/Sun and PUA domain-containing protein 1; NOL1/NOP2/Sun domain family member 6; NSUN6; NOPD1

Immunogen: Recombinant full length Human NSUN6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: