NTRK1 monoclonal Antibody | MB64269

NTRK1 monoclonal Antibody | MB64269 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:150

Background: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: neurotrophic receptor tyrosine kinase 1

Molecular Weight: 87.3 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA

Immunogen: Human recombinant protein fragment corresponding to amino acids 440-796 of human NTRK1 (NP_002520) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A