Description
NU-7026 is a potent DNA-PK inhibitor (IC₅₀ of 0.23 μM); displays 60-fold selectivity for DNA-PK than PI3K and inactive against both ATM and ATR.
NU-7026 is a potent DNA-PK inhibitor (IC₅₀ of 0.23 μM); displays 60-fold selectivity for DNA-PK than PI3K and inactive against both ATM and ATR.
Alternate Name/Synonyms: 2-(Morpholin-4-yl)-benzo[h]chromen-4-one; NU7026; NU 7026
Appearance: Crystalline solid
Formulation:
CAS Number: 154447-35-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₅NO₃
Molecular Weight: 281.31
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities: >2 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent specific DNA-PK inhibitor
MDL Number:
PubChem CID: 9860529
SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3
InChi: InChI=1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2
InChi Key: KKTZALUTXUZPSN-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12months |