NUP155 Antibody | 4703

NUP155 Antibody | 4703 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: Predicted species reactivity based on immunogen sequence: Rat: (100%)

Immunogen: NUP155 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NUP155.
The immunogen is located within the last 50 amino acids of NUP155.

Research Area: Homeostasis

Tested Application: E, WB

Application: NUP155 antibody can be used for detection of NUP155 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1286 - P815 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: NUP155 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: NUP155 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: NUP155 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: NUP155 Antibody: N155, KIAA0791, Nuclear pore complex protein Nup155, 155 kDa nucleoporin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: NUP155 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP) -155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF) , suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.