NUP50 Antibody| F40107-0.08ML/F40107-0.4ML/R33863-100UG

NUP50 Antibody| F40107-0.08ML/F40107-0.4ML/R33863-100UG | Gentaur UK, US & Europe Distribution

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: Rat

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NUP50 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Storage: Aliquot the NUP50 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A